Towards a molecular diagnosis of invasive aspergillosis and disseminated candidosis

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Disseminated invasive aspergillosis.

SummaryWe present a case of disseminated invasive aspergillosis in a young male adult with progressive complex gastrointestinal, non-specific peripheral neural and respiratory symptoms and subsequent acute haemorrhagic conjunctivitis and generalized dermatitis.The case emphasizes the difficulty in diagnosing systemic mycosis and a high index of suspicion is recommended particularly in patients ...

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Molecular approaches to diagnosis of invasive aspergillosis what we know and what we do not know.

Invasive aspergillosis (IA) are a major complication in immunocompromized patients where can be serious and rapidly fatal. Early diagnosis and early appropriate antifungal treatment is important in reducing mortality and morbidity. But despite many efforts to develop detection methods, the diagnosis of IA still remains challenging and current conventional methods are limited for adequate diagno...

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Laboratory diagnosis of invasive aspergillosis.

Invasive aspergillosis occurs in a wide range of clinical scenarios, is protean in its manifestations, and is still associated with an unacceptably high mortality rate. Early diagnosis is critical to a favourable outcome, but is difficult to achieve with current methods. Deep tissue diagnostic specimens are often difficult to obtain from critically ill patients. Newer antifungal agents exhibit ...

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molecular approaches to diagnosis of invasive aspergillosis what we know and what we do not know.

invasive aspergillosis (ia) are a major complication in immunocompromized patients where can be serious and rapidly fatal. early diagnosis and early appropriate antifungal treatment is important in reducing mortality and morbidity. but despite many efforts to develop detection methods, the diagnosis of ia still remains challenging and current conventional methods are limited for adequate diagno...

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ژورنال

عنوان ژورنال: FEMS Immunology & Medical Microbiology

سال: 2005

ISSN: 0928-8244,1574-695X

DOI: 10.1016/j.femsim.2005.05.012